Low-cost FC Stack Concept with Simplified Configuration Utilizing Advanced MEA and FC Module

Crosstalk between human <fc>DC</fc> subsets promotes antibacterial activity and <fc>CD</fc>8^#x0002B; <fc>T</fc>#x02010;cell stimulation in response to bacille <fc>C</fc>almette#x02010;<fc>G</fc>u#x000E9;rin

To date, little is known about the unique contributions of specialized human DC subsets to protection against tuberculosis (TB). Here, we focus on the role of human plasmacytoid (p)DCs and myeloid (m)DCs in the immune response to the TB vaccine bacille CalmetteGuérin (BCG). Ex vivo DC subsets from human peripheral blood were purified and infected with BCG expressing GFP to distinguish between i...

The Low Affinity Fc Receptor for IgG

Exposure to inflammatory cytokines selectively limits <fc>GM</fc><fc>CSF</fc> production by induced T regulatory cells

Interest in manipulating the immunosuppressive powers of Foxp3-expressing T regulatory cells as an immunotherapy has been tempered by their reported ability to produce proinflammatory cytokines when manipulated in vitro, or in vivo. Understanding processes that can limit this potentially deleterious effect of Treg cells in a therapeutic setting is therefore important. Here, we have studied this...

Experimental Investigation of Small Diameter Two - Phase Closed Thermosy - phons Charged with Water , FC - 84 , FC - 77 & FC - 3283

An experimental investigation of the performance of thermosyphons charged with water as well as the dielectric heat transfer liquids FC-84, FC-77 and FC-3283 has been carried out. The copper thermosyphon was 200 mm long with an inner diameter of 6 mm, which can be considered quite small compared with the vast majority of thermosyphons reported in the open literature. The evaporator length was 4...

Role of the Fc gamma R subclasses Fc gamma RII and Fc gamma RIII in the activation of human neutrophils by low and high valency immune complexes.

Two Fc gamma receptor (Fc gamma R) subclasses on human neutrophils, Fc gamma RII and Fc gamma RIII, activate different cellular functions. To examine the involvement of each receptor subtype in polymorphonuclear leukocyte activation, Fab and F(ab')2 fragments of subclass-specific monoclonal antibodies ([mAbs] mAb IV.3 against Fc gamma RII and mAb 3G8 against Fc gamma RIII, respectively) were us...